Oxaprozin potassium

TargetMol Chemicals

Oxaprozin potassium

65

174064-08-5

Chemical

Oxaprozin potassium

C18H14KNO3

331.412

Oxaprozin potassium is an orally active and potent inhibitor of COX, with IC 50 values of 2.2 uM and 36 uM for human platelet COX-1 and for IL-1-stimulated human synovial cell COX-2, respectively. Oxaprozin potassium induces cell apoptosis. Oxaprozin potassium also inhibits the NF-kappaB activation. Oxaprozin potassium-mediated inhibition of the Akt/IKK/NF-kappaB pathway contributes to its anti-inflammatory properties [1] [2].

3 years

[K+].[O-]C(=O)CCc1nc(c(o1)-c1ccccc1)-c1ccccc1

-20°

12352200