Oxcarbazepine [28721-07-5]
O9210
Estimated Purity≥98%
Product group Chemicals
Overview
- SupplierLKT Laboratories
- Product NameOxcarbazepine [28721-07-5]
- Delivery Days Customer7
- CertificationResearch Use Only
- Estimated Purity≥98%
- FormatSoluble in DMSO (9mg/mL).
- Scientific Descriptionalfa4bèta2 nAChR desensitizer, delayed-rectifier voltage-gated K+ and voltage-gated Na+ channel blocker.; Trileptal
- Storage InstructionAmbient
- UNSPSC12352200
References
- Di Resta C, Ambrosi P, Curia G, et al. Effect of carbamazepine and oxcarbazepine on wild-type and mutant neuronal nicotinic acetylcholine receptors linked to nocturnal frontal lobe epilepsy. Eur J Pharmacol. 2010 Sep 15;643(1):13-20. PMID: 20561518. Johannessen Landmark C, Johannessen SI. Pharmacological management of epilepsy: recent advances and future prospects. Drugs. 2008;68(14):1925-39. PMID: 18778117. Huang CW, Huang CC, Lin MW, et al. The synergistic inhibitory actions of oxcarbazepine on voltage-gated sodium and potassium currents in differentiated NG108-15 neuronal cells and model neurons. Int J Neuropsychopharmacol. 2008 Aug;11(5):597-610. PMID: 18184444. Sitges M, Chiu LM, Guarneros A, et al. Effects of carbamazepine, phenytoin, lamotrigine, oxcarbazepine, topiramate and vinpocetine on Na+ channel-mediated release of [3H]glutamate in hippocampal nerve endings. Neuropharmacology. 2007 Feb;52(2):598-605. PMID: 17070874. Nishimura M, Nakanishi T, Yasui A, et al. Serum calcium increases the incidence of arrhythmias during acetate hemodialysis. Am J Kidney Dis. 1992 Feb;19(2):149-55. PMID: 1739097.