P-gp inhibitor 14 [2892571-47-8]

TargetMol Chemicals

P-gp inhibitor 14 [2892571-47-8]

16

Research Use Only

C37H38N2O8

638.71

Compound 8a, also known as P-gp inhibitor 14, demonstrates high affinity as a P-gp inhibitor and effectively reverses P-gp-mediated multidrug resistance (EC 50 = 48.74 nM). Additionally, this compound exhibits a weak inhibitory effect on CYP3A4 activity [1].

O(C)C=1C2=C(C=3C=4C5=C(C(OC)=CC4CN(CC3C1)C6=CC=C(CCN7CC=8C(CC7)=CC(OC)=C(OC)C8)C=C6)OCO5)OCO2

-20°C

51202000