P-gp inhibitor 18

MedChem Express

P-gp inhibitor 18

14

Research Use Only

C42H65NO6

679.97

P-gp inhibitor 18 (compound 6G) is a potent inhibitor of P-glycoprotein (P-gp). P-gp inhibitor 18 inhibits rhodamine 123 (HY-D0816) efflux in the P-gp overexpressed leukemia cells, K562/Dox[1].

[H][C@]12CC[C@]3([C@@]([C@@]1(CC[C@]4(C(C)(C)[C@H](CC[C@]24C)O)[H])C)(C)CC[C@]5(CC[C@H]([C@@]53[H])C(C)=C)COC(NCCC6=CC(OC)=C(C(OC)=C6)OC)=O)[H]

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