P11149

MedChem Express

P11149 [164724-79-2]

10

164724-79-2

Research Use Only

99.23

C27H34ClNO4

472.02

P11149 is a competitive, BBB-penetarated weakly, orally active and selective inhibitor of AChE . P11149 exhibits an IC 50 of 1.3 microM for rat BChE/AChE. P11149, a Galanthamine derivative, demonstrates central cholinergic activity, behavioral efficacy and safety. P11149 is used in the study for Alzheimers disease [1] .

O=C(C12C[C@H](C3)C[C@H](C[C@H]3C2)C1)OC4=CC=C5C6=C4O[C@]7([H])[C@@]6(CCN(C)C5)C=C[C@H](O)C7.[H]Cl

2°C to 8°C

12352200