![p21 / WAF1(CIP1/823 + DCS-60.2), CF405S conjugate, 0.1mg/mL [26628-22-8] p21 / WAF1(CIP1/823 + DCS-60.2), CF405S conjugate, 0.1mg/mL [26628-22-8]](https://biotium.com/wp-content/uploads/2016/12/BNUB1135-0-1.jpg)
p21 / WAF1(CIP1/823 + DCS-60.2), CF405S conjugate, 0.1mg/mL [26628-22-8]
BNC041135
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityBovine, Human, Mouse
TargetCDKN1A
Overview
- SupplierBiotium
- Product Namep21 / WAF1(CIP1/823 + DCS-60.2), CF405S conjugate, 0.1mg/mL
- Delivery Days Customer9
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDCIP1/823 DCS-60.2
- Concentration0.1 mg/ml
- ConjugateOther Conjugate
- Gene ID1026
- Target nameCDKN1A
- Target descriptioncyclin dependent kinase inhibitor 1A
- Target synonymsCAP20; CDK-interacting protein 1; CDK-interaction protein 1; CDKN1; CIP1; cyclin-dependent kinase inhibitor 1; cyclin-dependent kinase inhibitor 1A (p21, Cip1); DNA synthesis inhibitor; MDA-6; melanoma differentiation associated protein 6; P21; p21CIP1; SDI1; WAF1; wild-type p53-activated fragment 1
- HostMouse
- IsotypeIgG
- Protein IDP38936
- Protein NameCyclin-dependent kinase inhibitor 1
- Scientific DescriptionThis MAb recognizes a 21 kDa protein, identified as the p21WAF1 tumor suppressor protein. This MAb is highly specific to p21 and shows no cross-reaction with other closely related mitotic inhibitors. p21WAF1 is a specific inhibitor of cdks and a tumor suppressor involved in the pathogenesis of a variety of malignancies. The expression of this gene acts as an inhibitor of the cell cycle during G1 phase and is tightly controlled by the tumor suppressor protein p53. Its expression is induced by the wild type, but not mutant, p53 suppressor protein. Normal cells generally display a rather intense nuclear p21 expression. Loss of p21 expression has been reported in many carcinomas (gastric carcinoma, non-small cell lung carcinoma, thyroid carcinoma).Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- SourceAnimal
- ReactivityBovine, Human, Mouse
- Storage Instruction2°C to 8°C
- UNSPSC12352203