p38-alpha MAPK-IN-5 [1443242-46-3]

TargetMol Chemicals

p38-alpha MAPK-IN-5 [1443242-46-3]

114

Chemical

Research Use Only

p38-alfa MAPK-IN-5

C37H49N11O2

679.86

P38-alpha MAPK-IN-5 is a potent inhibitor of p38alpha, demonstrating inhibitory concentrations (IC50) of 0.1 nM for p38alpha, 0.2 nM for p38beta, 944 nM for p38gamma, and 4100 nM for p38delta. It exhibits anti-inflammatory properties and holds potential for research in asthma and chronic obstructive pulmonary disease (COPD).

3 years

O(C1=CN2C(=NN=C2C=C1)N3[C@@H](C)CCCC3)[C@H]4C=5C([C@@H](NC(NC=6N(N=C(C(C)(C)C)C6)C7=CN(CCN(C)C)N=C7)=O)CC4)=CC=CC5

-20°C

51202000