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ICC/IF analysis of paraformaldehyde fixed A431 cells using GTX89145 P4HA1 antibody, Internal. Green : Primary antibody Blue : DAPI Negative control: Unimmunized goat IgG Dilution : 10microg/ml
ICC/IF analysis of paraformaldehyde fixed A431 cells using GTX89145 P4HA1 antibody, Internal. Green : Primary antibody Blue : DAPI Negative control: Unimmunized goat IgG Dilution : 10microg/ml
ICC/IF analysis of paraformaldehyde fixed A431 cells using GTX89145 P4HA1 antibody, Internal. Green : Primary antibody Blue : DAPI Negative control: Unimmunized goat IgG Dilution : 10microg/ml

P4HA1 antibody, Internal

Research Use Only
GTX89145
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Rat
TargetP4HA1
Price on request
Packing Size
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Overview

  • Supplier
    GeneTex
  • Product Name
    P4HA1 antibody, Internal
  • Delivery Days Customer
    9
  • Antibody Specificity
    This antibody is expected to recognise both reported isoforms (NP_000908.2 and NP_001017962.1).
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.50 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID5033
  • Target name
    P4HA1
  • Target description
    prolyl 4-hydroxylase subunit alpha 1
  • Target synonyms
    collagen prolyl 4-hydroxylase alpha(I); C-P4Halpha(I); P4HA; procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide I; procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-1; prolyl 4-hydroxylase subunit alpha-1; prolyl 4-hydroxylase, alpha polypeptide I
  • Host
    Goat
  • Isotype
    IgG
  • Scientific Description
    This gene encodes a component of prolyl 4-hydroxylase, a key enzyme in collagen synthesis composed of two identical alpha subunits and two beta subunits. The encoded protein is one of several different types of alpha subunits and provides the major part of the catalytic site of the active enzyme. In collagen and related proteins, prolyl 4-hydroxylase catalyzes the formation of 4-hydroxyproline that is essential to the proper three-dimensional folding of newly synthesized procollagen chains. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
  • Reactivity
    Human, Rat
  • Storage Instruction
    2°C to 8°C,-20°C or -80°C
  • UNSPSC
    12352203

References

  • Overexpression of P4HA1 associates with poor prognosis and promotes cell proliferation and metastasis of lung adenocarcinoma. Ning Y et al., 2021, J Cancer
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  • HIF-mediated metabolic switching in bladder outlet obstruction mitigates the relaxing effect of mitochondrial inhibition. Ekman M et al., 2014 May, Lab Invest
    Read more