p53 Activator 7

MedChem Express

p53 Activator 7

10

Research Use Only

98.52

C27H32F3N4OP

516.54

p53 Activator 7 is a p53 mutation Y220C (MDM-2/p53) activator with an EC 50 of 104 nM. p53 Activator 7 can bind to p53 mutant and restore its ability to bind DNA (WO2022213975A1; Example B-1) [1] . p53 Activator 7 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

FC(F)(F)CN1C2=C(C(NC3CCN(CC3)C)=CC=C2)C=C1C#CCNC4=CC=C(P(C)(C)=O)C=C4

2°C to 8°C

12352200