WB analysis of various samples using GTX00681 p53 (phospho Ser20) antibody [17B6] (upper panel) or anti-p53 antibody (lower panel). All samples were immunoprecipitated with anti-Flag antibody and then analyzed by Western blot. Left : H1299 cells transfected with Flag vector Middle : H1299 cells transfected with Flag-p53 (wild-type) Right : H1299 cells transfected with Flag-p53 mutant (Ser20Ala).
WB analysis of various samples using GTX00681 p53 (phospho Ser20) antibody [17B6] (upper panel) or anti-p53 antibody (lower panel). All samples were immunoprecipitated with anti-Flag antibody and then analyzed by Western blot. Left : H1299 cells transfected with Flag vector Middle : H1299 cells transfected with Flag-p53 (wild-type) Right : H1299 cells transfected with Flag-p53 mutant (Ser20Ala).
p53 (phospho Ser20) antibody [17B6]
GTX00681
Overview
- SupplierGeneTex
- Product Namep53 (phospho Ser20) antibody [17B6]
- Delivery Days Customer9
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID17B6
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID7157
- Target nameTP53
- Target descriptiontumor protein p53
- Target synonymsantigen NY-CO-13; BCC7; BMFS5; cellular tumor antigen p53; LFS1; mutant tumor protein 53; P53; p53 tumor suppressor; phosphoprotein p53; transformation-related protein 53; TRP53; tumor protein 53; tumor supressor p53
- HostMouse
- IsotypeIgG1
- Modification TypePhosphorylated
- Scientific DescriptionThis gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016]
- ReactivityHuman
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC12352203