p53 Polyclonal Antibody

Reddot Biotech

p53 Polyclonal Antibody

5

ImmunoFluorescence

Research Use Only

1 mg/ml

Unconjugated

Trp53

transformation related protein 53

bbl; bfy; bhy; cellular tumor antigen p53; ME-delta123p53; mutant p53; p4; p44; p5; p53; p53 cellular tumor antigen; Tp53; tumor suppressor p53; tumor supressor p53

Rabbit

IgG

This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277).

Human, Mouse, Rat

-20°C

12352203