
ICC/IF analysis of methanol-fixed HeLa cells using GTX50304 p70 S6K (phospho Ser424) antibody.
p70 S6K (phospho Ser424) antibody

GTX50304
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetRPS6KB1
Overview
- SupplierGeneTex
- Product Namep70 S6K (phospho Ser424) antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:1000. ICC/IF: 1:100-1:200. IHC-P: 1:50-1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- FormulationLiquid
- Gene ID6198
- Target nameRPS6KB1
- Target descriptionribosomal protein S6 kinase B1
- Target synonymsp70 S6KA; p70(S6K)-alpha; p70-alpha; p70-S6K; PS6K; ribosomal protein S6 kinase beta-1; ribosomal protein S6 kinase I; ribosomal protein S6 kinase, 70kDa, polypeptide 1; S6K; S6K1; S6K-beta-1; serine/threonine kinase 14 alpha; serine/threonine-protein kinase 14A; STK14A
- HostRabbit
- IsotypeIgG
- Modification TypePhosphorylated
- Protein IDP23443
- Protein NameRibosomal protein S6 kinase beta-1
- Scientific DescriptionThis gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17. [provided by RefSeq, Jan 2013]
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Metformin triggers the intrinsic apoptotic response in human AGS gastric adenocarcinoma cells by activating AMPK and suppressing mTOR/AKT signaling. Lu CC et al., 2019 Apr, Int J OncolRead more
- Tripartite motif 32 prevents pathological cardiac hypertrophy. Chen L et al., 2016 May 1, Clin Sci (Lond)Read more