ICC/IF analysis of HeLa cells using GTX11997 p73 delta N antibody [38C674.2]. Green : primary antibody Red : Actin Blue : DAPI Dilution : 1:50 Fixation : 10% formalin Permibilization : 0.5% Triton-X100
![IHC-Fr analysis of E15 (A) and E17 (B) rat embryonic kidney tissue using GTX11997 p73 delta N antibody [38C674.2]. Delta Np73 is expressed in ureteric bud (UB) branches, and metanephrogenic mesenchyme (MM), as well as in cells invading the glomerular cleft. DeltaNp73 is expressed in the ureteric bud (UB) branches, metanephrogenic mesenchyme (MM), and nephron progenitors. Dilution : 1:2000](https://www.genetex.com/upload/website/prouct_img/normal/GTX11997/GTX11997_358_IHC-Fr_w_23060519_664.webp "IHC-Fr analysis of E15 (A) and E17 (B) rat embryonic kidney tissue using GTX11997 p73 delta N antibody [38C674.2]. Delta Np73 is expressed in ureteric bud (UB) branches, and metanephrogenic mesenchyme (MM), as well as in cells invading the glomerular cleft. DeltaNp73 is expressed in the ureteric bud (UB) branches, metanephrogenic mesenchyme (MM), and nephron progenitors. Dilution : 1:2000")
![IHC-P analysis of human lung squamous cell carcinoma tissue using GTX11997 p73 delta N antibody [38C674.2]. Dilution : 5 microg/ml](https://www.genetex.com/upload/website/prouct_img/normal/GTX11997/GTX11997_380_IHC-P_w_23060519_773.webp "IHC-P analysis of human lung squamous cell carcinoma tissue using GTX11997 p73 delta N antibody [38C674.2]. Dilution : 5 microg/ml")
![IHC-P analysis of human placenta tissue using GTX11997 p73 delta N antibody [38C674.2]. Dilution : 5 microg/ml Antigen retrieval : Heat-induced antigen retrieval](https://www.genetex.com/upload/website/prouct_img/normal/GTX11997/GTX11997_381_IHC-P_w_23060519_484.webp "IHC-P analysis of human placenta tissue using GTX11997 p73 delta N antibody [38C674.2]. Dilution : 5 microg/ml Antigen retrieval : Heat-induced antigen retrieval")
![WB analysis of (A) p73 delta N overexpressing (B) HeLa, and (C) NIH-3T3 cell lysate using GTX11997 p73 delta N antibody [38C674.2]. Dilution : 1 microg/ml](https://www.genetex.com/upload/website/prouct_img/normal/GTX11997/GTX11997_903_WB_w_23060519_348.webp "WB analysis of (A) p73 delta N overexpressing (B) HeLa, and (C) NIH-3T3 cell lysate using GTX11997 p73 delta N antibody [38C674.2]. Dilution : 1 microg/ml")
ICC/IF analysis of HeLa cells using GTX11997 p73 delta N antibody [38C674.2]. Green : primary antibody Red : Actin Blue : DAPI Dilution : 1:50 Fixation : 10% formalin Permibilization : 0.5% Triton-X100
p73 delta N antibody [38C674.2]
GTX11997
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
Overview
- SupplierGeneTex
- Product Namep73 delta N antibody [38C674.2]
- Delivery Days Customer7
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID38C674.2
- Concentration1 mg/ml
- ConjugateUnconjugated
- HostMouse
- IsotypeIgG1
- Scientific DescriptionEven though the tumor suppressor gene p53 is highly important in human cancer, as indicated by the fact that it is mutated in about 50% of cases, up to a few years ago no similar proteins had been identified. Two p53 homologues are now identified, p73 and p63, with high amino acid identity suggesting similar functions. Both p63 and p73 have two significant structural peculiarities compared with p53; the presence of an extended non-conserved C-terminus containing a sterile alpha motive (SAM), (typical of developmental proteins), and the presence of number of different splicing isoforms differing in the N-terminus or in the absence of the transactivation domain (delta N forms).
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203