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Pacritinib

ORB181302
Biorbyt
CAS Number937272-79-2
Product group Chemicals
Molecular Weight472.58
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Overview

  • Supplier
    Biorbyt
  • Product Name
    Pacritinib [937272-79-2]
  • Delivery Days Customer
    16
  • CAS Number
    937272-79-2
  • Molecular Formula
    C28H32N4O3
  • Molecular Weight
    472.58
  • Scientific Description
    Pacritinib (SB1518) is a potent and selective JAK2 (IC50 = 23 and 19 nM for JAK2WT and JAK2V617F, respectively) and FLT3 (IC(50) = 22 nM) inhibitor with selectivity against JAK1 and JAK3 (IC50= 1280 and 520 nM, respectively).
  • SMILES
    C1(COC/C=C/COCC2=C(OCCN3CCCC3)C=CC4=C2)=CC=CC(C5=N/C(NC=C5)=N4)=C1
  • UNSPSC
    12352200