PAI-RBP1 / SERBP1 / SERPINE1(SERBP1/3491), CF405S conjugate, 0.1mg/mL [26628-22-8]

Biotium

PAI-RBP1 / SERBP1 / SERPINE1(SERBP1/3491), CF405S conjugate, 0.1mg/mL

9

Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

SERBP1/3491

0.1 mg/ml

Other Conjugate

SERBP1

SERPINE1 mRNA binding protein 1

CGI-55; CHD3IP; chromodomain helicase DNA binding protein 3 interacting protein; HABP4L; PAI-1 mRNA binding protein; PAI1 RNA-binding protein 1; PAIRBP1; PAI-RBP1; plasminogen activator inhibitor 1 RNA-binding protein

Mouse

IgG1

Plasminogen activator inhibitor 1 RNA-binding protein

PAI-RBP1 (plasminogen activator inhibitor 1 RNA-binding protein), also known as SERBP1 (SERPINE1 mRNA-binding protein 1), CGI-55, CHD3IP (chromodomain helicase DNA binding protein 3 interacting protein), HABP4L or PAI-RBP1, is a membrane-associated protein that localizes to the nucleus, the perinuclear region of the cytoplasm and the plasma membrane. PAI-RBP1 is believed to play a role in the regulation of mRNA stability, as it specifically binds to the CRS (cyclic nucleotide-responsive sequence) motif of the PAI-1 mRNA and acts to stabilize the mRNA and regulate its expression. In addition, PAI-RBP1 interacts with Mi2- and may be involved in chromatin remodeling. PAI-RBP1 also interacts with PGRMC1 and participates in the transduction of Progesterones antiapoptotic action in ovarian cell types. The gene encoding PAI-RBP1 is overexpressed in ovarian cancer, suggesting a possible role for PAI-RBP1 in tumorigenesis and tumor metastasis. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Animal

Human

2°C to 8°C

12352203