PAIR2 [2771006-54-1]

TargetMol Chemicals

PAIR2 [2771006-54-1]

114

Chemical

Research Use Only

PAIR2

C27H26F4N6O3S

590.59

PAIR2 is a potent, selective partial antagonist of IRE1alpha RNase, effectively occupying the ATP-binding site of IRE1alpha in cells. This action prevents a potent KIRA from inhibiting XBP1 splicing [1].

3 years

O(C=1C2=C(C(NS(CC(F)(F)F)(=O)=O)=C(F)C1C)C=CC=C2)C3=C(C=CC=N3)C4=NC(N[C@H]5CCCNC5)=NC=C4

-20°C

12352200