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Western blot analysis of extracts from rat heart, using PAK3 (Ab-154) antibody.
Western blot analysis of extracts from rat heart, using PAK3 (Ab-154) antibody.
Western blot analysis of extracts from rat heart, using PAK3 (Ab-154) antibody.

PAK3 (Ab-154) Antibody

Research Use Only
CSB-PA554964
Cusabio
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman
TargetPAK3
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Overview

  • Supplier
    Cusabio
  • Product Name
    PAK3 (Ab-154) Antibody
  • Delivery Days Customer
    20
  • Applications
    Western Blot, ELISA
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID5063
  • Target name
    PAK3
  • Target description
    p21 (RAC1) activated kinase 3
  • Target synonyms
    adriamycin resistance-associated; ARA; beta-PAK; bPAK; MRX30; MRX47; oligophrenin-3; OPHN3; p21 (CDKN1A)-activated kinase 3; p21 protein (Cdc42/Rac)-activated kinase 3; PAK-3; PAK3beta; serine/threonine-protein kinase PAK 3; XLID30
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDO75914
  • Protein Name
    Serine/threonine-protein kinase PAK 3
  • Scientific Description
    Serine/threonine protein kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell migration, or cell cycle regulation. Plays a role in dendrite spine morphogenesis as well as synapse formation and plasticity. Acts as downstream effector of the small GTPases CDC42 and RAC1. Activation by the binding of active CDC42 and RAC1 results in a conformational change and a subsequent autophosphorylation on several serine and/or threonine residues. Phosphorylates MAPK4 and MAPK6 and activates the downstream target MAPKAPK5, a regulator of F-actin polymerization and cell migration. Additionally, phosphorylates TNNI3/troponin I to modulate calcium sensitivity and relaxation kinetics of thin myofilaments. May also be involved in early neuronal development. Allen K.M., Nat. Genet. 20:25-30(1998). Jiang C., Submitted (MAY-2000) to the EMBL/GenBank/DDBJ databases. Kitano T., Mol. Biol. Evol. 20:1281-1289(2003).
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C
  • UNSPSC
    12352203