Palbociclib [571190-30-2]
P014442
Estimated Purity≥98%
Product group Chemicals
Overview
- SupplierLKT Laboratories
- Product NamePalbociclib [571190-30-2]
- Delivery Days Customer7
- CertificationResearch Use Only
- Estimated Purity≥98%
- FormatSoluble in DMSO
- Scientific DescriptionCDK4/6 inhibitor.; PD-0332991, PD0332991, Ibrance
- Storage Instruction-20°C
- UNSPSC12352200
References
- Logan JE, Mostofizadeh N, Desai AJ, et al. PD-0332991, a Potent and Selective Inhibitor of Cyclin-dependent Kinase 4/6, Demonstrates Inhibition of Proliferation in Renal Cell Carcinoma at Nanomolar Concentrations and Molecular Markers Predict for Sensitivity. Anticancer Res. 2013 Aug;33(8):2997-3004. PMID: 23898052. Roberts PJ, Bisi JE, Strum JC, et al. Multiple roles of cyclin-dependent kinase 4/6 inhibitors in cancer therapy. J Natl Cancer Inst. 2012 Mar 21;104(6):476-87. PMID: 22302033. Rivadeneira DB, Mayhew CN, Thangavel C, et al. Proliferative suppression by CDK4/6 inhibition: complex function of the retinoblastoma pathway in liver tissue and hepatoma cells. Gastroenterology. 2010 May;138(5):1920-30. PMID: 20100483.