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ProductsBack/Palbociclib Isethionate [827022-33-3]

Palbociclib Isethionate [827022-33-3]

Research Use Only
P0344
LKT Laboratories
Estimated Purity≥98%
Product group Chemicals
€ 138,00
10 mg
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Overview

  • Supplier
    LKT Laboratories
  • Product Name
    Palbociclib Isethionate [827022-33-3]
  • Delivery Days Customer
    7
  • Certification
    Research Use Only
  • Estimated Purity
    ≥98%
  • Format
    Water 10 mg/mL warmed (17.43 mM); DMSO Insoluble; Ethanol Insoluble
  • Scientific Description
    CDK4/6 inhibitor.; PD0332991-0054, PF00080665-73
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • Vaughn DJ, Hwang W, Lal P, et al. Phase 2 trial of the cyclin-dependent kinase 4/6 inhibitor palbociclib in patients with retinoblastoma protein-expressing germ cell tumors. Cancer. 2014 Dec 18. [Epub ahead of print]. PMID: 25522918. DiRocco DP, Bisi J, Roberts P, et al. CDK4/6 inhibition induces epithelial cell cycle arrest and ameliorates acute kidney injury. Am J Physiol Renal Physiol. 2014 Feb 15;306(4):F379-88. PMID: 24338822. Barton KL, Misuraca K, Cordero F, et al. PD-0332991, a CDK4/6 inhibitor, significantly prolongs survival in a genetically engineered mouse model of brainstem glioma. PLoS One. 2013 Oct 2;8(10):e77639. PMID: 24098593. Fry DW, Harvey PJ, Keller PR, et al. Specific inhibition of cyclin-dependent kinase 4/6 by PD 0332991 and associated antitumor activity in human tumor xenografts. Mol Cancer Ther. 2004 Nov;3(11):1427-38. PMID: 15542782.