Palmatine (hydroxide)
HY-N0110B
Overview
- SupplierMedChem Express
- Product NamePalmatine (hydroxide)
- Delivery Days Customer5
- CertificationResearch Use Only
- Estimated Purity99.64
- Molecular FormulaC21H23NO5
- Molecular Weight369.41
- Scientific DescriptionPalmatine hydroxide is an orally active and irreversible indoleamine 2,3-dioxygenase 1 (IDO-1) inhibitor with IC 50 s of 3 microM and 157microM against HEK 293-hIDO-1 and rhIDO-1, respectively. Palmatine hydroxide can also inhibit West Nile virus (WNV) NS2B-NS3 protease in an uncompetitive manner with an IC 50 of 96 microM. Palmatine hydroxide shows anti-cancer, anti-oxidation, anti-inflammatory, neuroprotection, antibacterial, anti-viral activities [1] [2] [3] [4] [5] .
- SMILESCOC(C=C1C2=CC3=CC=C4OC)=C(C=C1CC[N+]2=CC3=C4OC)OC.[OH-]
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200