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Pamidronate (disodium) (Standard)

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MedChem Express
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Pamidronate (disodium) (Standard)
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Scientific Description
    Pamidronate disodium (Standard) is the analytical standard of Pamidronate disodium.Pamidronate disodium (Standard), the second-generation nitrogen-containing bisphosphonate, is an inhibitor of bone loss. Pamidronate disodium (Standard) significantly inhibits subchondral bone loss in early osteoarthritis by upregulating the expression of OPG in cartilage and subchondral bone, and inhibiting the expression of RANKL and MMP-9 in both tissues, as well as TLR-4 in cartilage, thereby alleviating cartilage degeneration. Additionally, Pamidronate disodium (Standard) can inhibit the signaling of Wnt and beta-catenin , and is applicable for research on osteoporosis and osteosarcoma [1] [2] [3] [4] .
  • UNSPSC
    41116135