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Pamidronic acid (sodium)

HY-B0012B
MedChem Express
Molecular Weight257.05
Product group Chemicals
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Pamidronic acid (sodium)
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Molecular Formula
    C3H10NNaO7P2
  • Molecular Weight
    257.05
  • Scientific Description
    Pamidronic acid sodium, the second-generation nitrogen-containing bisphosphonate, is an inhibitor of bone loss. Pamidronic acid sodium significantly inhibits subchondral bone loss in early osteoarthritis by upregulating the expression of OPG in cartilage and subchondral bone, and inhibiting the expression of RANKL and MMP-9 in both tissues, as well as TLR-4 in cartilage, thereby alleviating cartilage degeneration. Additionally, Pamidronic acid sodium can inhibit the signaling of Wnt and beta-catenin , and is applicable for research on osteoporosis and osteosarcoma [1] [2] [3] [4] .
  • SMILES
    O=P(O)(O[Na])C(O)(CCN)P(O)(O)=O
  • UNSPSC
    12352200