pan Cytokeratin antibody [C-11] (FITC)
GTX11212
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityAmphibian, Bovine, Human, Mammals, Mouse, Rat
Overview
- SupplierGeneTex
- Product Namepan Cytokeratin antibody [C-11] (FITC)
- Delivery Days Customer10
- ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDC-11
- HostMouse
- IsotypeIgG
- Scientific DescriptionGT211212 is a broad spectrum antibody which reacts specifically with a wide variety of normal, reactive and neoplastic epithelial tissues. The antibody reacts with simple, cornifying and non-cornifying squamous epithelia and pseudostratified epithelia. It does not react with non-epithelial normal human tissues. This antibody can be applied to methanol- or acetone-fixed frozen sections, and to formalin-fixed, paraffin-embedded human tissues. Increased staining intensity is seen following proteolytic treatment of tested tissue (protease iunmaskingi). Similarly embedded methacarn-fixed material is also suitable for cytokeratin demonstration. Anti-Pan Cytokeratin exhibits a wide interspecies cross-reactivity down to xenopus laevis (e.g., human, bovine, rat, and frog). GT211212 may be used for the localization of cytokeratins using various immunochemical assays including direct immunofluorescence using frozen or fixed tissue sections or cultured cells. It may also be used in flow cytometry of normal and neoplastic epithelial cells. Intermediate-sized filaments are abundant cytoplasmic structural proteins in most vertebrate cells.
- ReactivityAmphibian, Bovine, Human, Mammals, Mouse, Rat
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- Detection of ESR1 Mutations in Single Circulating Tumor Cells on Estrogen Deprivation Therapy but Not in Primary Tumors from Metastatic Luminal Breast Cancer Patients. Franken A et al., 2020 Jan, J Mol DiagnRead more
- EpCAM-Independent Enrichment of Circulating Tumor Cells in Metastatic Breast Cancer. Schneck H et al., 2015, PLoS OneRead more
- Fabrication and Characterization of 3D Bioprinted Triple-layered Human Alveolar Lung Models. Ng WL et al., 2021, Int J BioprintRead more
- Gene expression profiling of single circulating tumor cells in ovarian cancer - Establishment of a multi-marker gene panel. Blassl C et al., 2016 Aug, Mol OncolRead more
- Isolation and characterization of circulating tumor cells using a novel workflow combining the CellSearch® system and the CellCelector™. Neumann MH et al., 2017 Jan, Biotechnol ProgRead more