![IHC-P analysis of human placenta sections using GTX26401 pan Cytokeratin antibody [PCK-26] at 1:300. IHC-P analysis of human placenta sections using GTX26401 pan Cytokeratin antibody [PCK-26] at 1:300.](https://www.genetex.com/upload/website/prouct_img/normal/GTX26401/GTX26401_20170605_IHC-P_w_23060722_827.webp)
IHC-P analysis of human placenta sections using GTX26401 pan Cytokeratin antibody [PCK-26] at 1:300.
pan Cytokeratin antibody [PCK-26]
GTX26401
ApplicationsDot Blot, Flow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin, Neutralisation/Blocking, Other Application
Product group Antibodies
ReactivityBovine, Canine, Chicken, Feline, Fish, Guinea Pig, Goat, Hamster, Human, Mouse, Porcine, Rabbit, Reptile, Rat, Sheep
Overview
- SupplierGeneTex
- Product Namepan Cytokeratin antibody [PCK-26]
- Delivery Days Customer9
- Antibody SpecificityThe antibody recognizes an epitope located on the Type II cytokeratins 1, 5, 6, and 8. PCK-26 is a broad spectrum antibody which reacts specifically with a variety of normal, reactive, and neoplastic epithelial tissues. The antibody reacts with simple, co
- Application Supplier NoteIHC-P: 1:300. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsDot Blot, Flow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin, Neutralisation/Blocking, Other Application
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDPCK-26
- ConjugateUnconjugated
- HostMouse
- IsotypeIgG1
- Scientific DescriptionCytokeratins, a group comprising at least 29 different proteins, are characteristic of epithelial and trichocytic cells. Cytokeratin 5, 6 and 8 are members of the type II neutral-to-basic subfamily. Monoclonal antibodies to cytokeratins are specific markers of epithelial cell differentiation and have been widely used as tools in tumor identification and classification. PCK-26 facilitates the typing of normal, metaplastic and neoplastic cells and it may aid in the discrimination of carcinomas and non-epithelial tumors such as sarcomas, lymphomas and neural tumors. It is also useful in detecting micro-metastases in lymph nodes and other tissues and for determining the origin of poorly differentiated tumors (1,2).
- ReactivityBovine, Canine, Chicken, Feline, Fish, Guinea Pig, Goat, Hamster, Human, Mouse, Porcine, Rabbit, Reptile, Rat, Sheep
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Preneoplastic stromal cells promote BRCA1-mediated breast tumorigenesis.Read more
- Changes in plasma circulating microvesicles in patients with HCV-related cirrhosis after treatment with direct-acting antivirals. Campello E et al., 2020 Apr, Liver IntRead more
- Chymase-producing cells of the innate immune system are required for decidual vascular remodeling and fetal growth. Meyer N et al., 2017 Mar 22, Sci RepRead more
- Suppression of Tumor Growth and Muscle Wasting in a Transgenic Mouse Model of Pancreatic Cancer by the Novel Histone Deacetylase Inhibitor AR-42. Henderson SE et al., 2016 Dec, NeoplasiaRead more
- Stable SET knockdown in head and neck squamous cell carcinoma promotes cell invasion and the mesenchymal-like phenotype in vitro, as well as necrosis, cisplatin sensitivity and lymph node metastasis in xenograft tumor models. Sobral LM et al., 2014 Feb 20, Mol CancerRead more
- Functional heterogeneity of cancer-associated fibroblasts from human colon tumors shows specific prognostic gene expression signature. Herrera M et al., 2013 Nov 1, Clin Cancer ResRead more
- beta-catenin functions pleiotropically in differentiation and tumorigenesis in mouse embryo-derived stem cells. Okumura N et al., 2013, PLoS OneRead more
- The use of allodermis prepared from Euro skin bank to prepare autologous tissue engineered skin for clinical use. Deshpande P et al., 2013 Sep, BurnsRead more
- beta2 integrin-mediated cell-cell contact transfers active myeloperoxidase from neutrophils to endothelial cells. Jerke U et al., 2013 May 3, J Biol ChemRead more
- Mammalian innate resistance to highly pathogenic avian influenza H5N1 virus infection is mediated through reduced proinflammation and infectious virus release. Nelli RK et al., 2012 Sep, J VirolRead more