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IHC-P analysis of human placenta sections using GTX26401 pan Cytokeratin antibody [PCK-26] at 1:300.
IHC-P analysis of human placenta sections using GTX26401 pan Cytokeratin antibody [PCK-26] at 1:300.
IHC-P analysis of human placenta sections using GTX26401 pan Cytokeratin antibody [PCK-26] at 1:300.

pan Cytokeratin antibody [PCK-26]

GTX26401
GeneTex
ApplicationsDot Blot, Flow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin, Neutralisation/Blocking, Other Application
Product group Antibodies
ReactivityBovine, Canine, Chicken, Feline, Fish, Guinea Pig, Goat, Hamster, Human, Mouse, Porcine, Rabbit, Reptile, Rat, Sheep
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Overview

  • Supplier
    GeneTex
  • Product Name
    pan Cytokeratin antibody [PCK-26]
  • Delivery Days Customer
    9
  • Antibody Specificity
    The antibody recognizes an epitope located on the Type II cytokeratins 1, 5, 6, and 8. PCK-26 is a broad spectrum antibody which reacts specifically with a variety of normal, reactive, and neoplastic epithelial tissues. The antibody reacts with simple, co
  • Application Supplier Note
    IHC-P: 1:300. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Dot Blot, Flow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin, Neutralisation/Blocking, Other Application
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    PCK-26
  • Conjugate
    Unconjugated
  • Host
    Mouse
  • Isotype
    IgG1
  • Scientific Description
    Cytokeratins, a group comprising at least 29 different proteins, are characteristic of epithelial and trichocytic cells. Cytokeratin 5, 6 and 8 are members of the type II neutral-to-basic subfamily. Monoclonal antibodies to cytokeratins are specific markers of epithelial cell differentiation and have been widely used as tools in tumor identification and classification. PCK-26 facilitates the typing of normal, metaplastic and neoplastic cells and it may aid in the discrimination of carcinomas and non-epithelial tumors such as sarcomas, lymphomas and neural tumors. It is also useful in detecting micro-metastases in lymph nodes and other tissues and for determining the origin of poorly differentiated tumors (1,2).
  • Reactivity
    Bovine, Canine, Chicken, Feline, Fish, Guinea Pig, Goat, Hamster, Human, Mouse, Porcine, Rabbit, Reptile, Rat, Sheep
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

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  • Changes in plasma circulating microvesicles in patients with HCV-related cirrhosis after treatment with direct-acting antivirals. Campello E et al., 2020 Apr, Liver Int
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  • Chymase-producing cells of the innate immune system are required for decidual vascular remodeling and fetal growth. Meyer N et al., 2017 Mar 22, Sci Rep
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  • Suppression of Tumor Growth and Muscle Wasting in a Transgenic Mouse Model of Pancreatic Cancer by the Novel Histone Deacetylase Inhibitor AR-42. Henderson SE et al., 2016 Dec, Neoplasia
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  • Stable SET knockdown in head and neck squamous cell carcinoma promotes cell invasion and the mesenchymal-like phenotype in vitro, as well as necrosis, cisplatin sensitivity and lymph node metastasis in xenograft tumor models. Sobral LM et al., 2014 Feb 20, Mol Cancer
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  • Functional heterogeneity of cancer-associated fibroblasts from human colon tumors shows specific prognostic gene expression signature. Herrera M et al., 2013 Nov 1, Clin Cancer Res
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  • beta-catenin functions pleiotropically in differentiation and tumorigenesis in mouse embryo-derived stem cells. Okumura N et al., 2013, PLoS One
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  • The use of allodermis prepared from Euro skin bank to prepare autologous tissue engineered skin for clinical use. Deshpande P et al., 2013 Sep, Burns
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  • beta2 integrin-mediated cell-cell contact transfers active myeloperoxidase from neutrophils to endothelial cells. Jerke U et al., 2013 May 3, J Biol Chem
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  • Mammalian innate resistance to highly pathogenic avian influenza H5N1 virus infection is mediated through reduced proinflammation and infectious virus release. Nelli RK et al., 2012 Sep, J Virol
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