pan-HCN-IN-1

MedChem Express

pan-HCN-IN-1

5

Research Use Only

C23H37N3O2

387.56

pan-HCN-IN-1 (Compound J&J12e) is an inhibitor for hyperpolarization-activated and cyclic-nucleotide-gated 1 (HCN1) ion channel, with IC50 of 58 nM. pan-HCN-IN-1 reduces the voltage sag response and enhances EPSP summation in ex vivo rats brain slices[1].

CCOC1=CC=CC=C1C(NCC2(CCCCC2)N3CCN(CC3)C(C)C)=O

12352200