pan-KRAS-IN-6 [3033565-36-2]

TargetMol Chemicals

pan-KRAS-IN-6 [3033565-36-2]

9

Research Use Only

C29H30ClF3N6O3S

635.1

Pan-KRAS-IN-6 (compound 12) is a potent pan-KRAS inhibitor, with IC50 values of 9.79 nM for Kras G12D and 6.03 nM for Kras G12V.

C(OC=1N=C(C2=C(N1)C(F)=C(C(Cl)=C2)C3=C4C(SC(N)=N4)=C(F)C=C3)N5CC(C)(O)COCC5)[C@@]67N(C[C@H](F)C6)CCC7

-20°C

51202000