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Panobinostat

T2383
TargetMol Chemicals
CAS Number404950-80-7
Product group Chemicals
Molecular Weight349.43
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    Panobinostat
  • Delivery Days Customer
    4
  • CAS Number
    404950-80-7
  • Category Supplier
    Chemical
  • Chemical Name
    Panobinostat
  • Molecular Formula
    C21H23N3O2
  • Molecular Weight
    349.43
  • Scientific Description
    Panobinostat (NVP-LBH589) is a broad-spectrum HDAC inhibitor (IC50=5 nM) with oral activity and non-selectivity. Panobinostat has antitumor activity and induces apoptosis and autophagy.
  • Shelf life instruction
    3 years
  • SMILES
    C(CNCC1=CC=C(/C=C/C(NO)=O)C=C1)C=2C=3C(NC2C)=CC=CC3
  • Storage Instruction
    -20°
  • UNSPSC
    12352200

References

  • Crisanti MC, et al. The HDAC inhibitor panobinostat (LBH589) inhibits mesothelioma and lung cancer cells in vitro and in vivo with particular efficacy for small cell lung cancer. Mol Cancer Ther. 2009 Aug;8(8):2221-31.
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