WB analysis of various sample lysates using GTX33386 PARN antibody. Dilution : 1:1000 Loading : 25microg per lane
WB analysis of various sample lysates using GTX33386 PARN antibody. Dilution : 1:1000 Loading : 25microg per lane
PARN antibody
GTX33386
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
Product group Antibodies
ReactivityHuman
TargetPARN
Overview
- SupplierGeneTex
- Product NamePARN antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500 - 1:2000. ICC/IF: 1:50 - 1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID5073
- Target namePARN
- Target descriptionpoly(A)-specific ribonuclease
- Target synonymsDAN; deadenylating nuclease; deadenylation nuclease; DKCB6; PFBMFT4; poly(A)-specific ribonuclease PARN; polyadenylate-specific ribonuclease
- HostRabbit
- IsotypeIgG
- Protein IDO95453
- Protein NamePoly(A)-specific ribonuclease PARN
- Scientific DescriptionThe protein encoded by this gene is a 3-exoribonuclease, with similarity to the RNase D family of 3-exonucleases. It prefers poly(A) as the substrate, hence, efficiently degrades poly(A) tails of mRNAs. Exonucleolytic degradation of the poly(A) tail is often the first step in the decay of eukaryotic mRNAs. This protein is also involved in silencing of certain maternal mRNAs during oocyte maturation and early embryonic development, as well as in nonsense-mediated decay (NMD) of mRNAs that contain premature stop codons. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203