PARP-2/1-IN-2

MedChem Express

PARP-2/1-IN-2

10

Research Use Only

C13H16N4O

244.29

PARP-2/1-IN-2 (Compound 4a), the enantiomer of Veliparib (HY-10129), is a potent PARP inhibitor with K i s of 2 and 5 nM against PARP-2 and PARP-1 , respectively. PARP-2/1-IN-2 has an EC 50 of 3 nM in a cell based assay of PARP activity [1] .

NC(C1=C2C(N=C([C@]3(C)CCCN3)N2)=CC=C1)=O

12352200