PATJ antibody [N1], N-term
GTX104753
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman, Mouse
TargetPATJ
Overview
- SupplierGeneTex
- Product NamePATJ antibody [N1], N-term
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID10207
- Target namePATJ
- Target descriptionPATJ crumbs cell polarity complex component
- Target synonymsCipp, INADL, InaD-like, hINADL, inaD-like protein, PALS1-associated tight junction protein, PDZ domain protein, channel-interacting PDZ domain protein, channel-interacting PDZ domain-containing protein, inactivation no after-potential D-like protein, inactivation-no-afterpotential D-like, protein associated to tight junctions
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThis gene encodes a protein with multiple PDZ domains. PDZ domains mediate protein-protein interactions, and proteins with multiple PDZ domains often organize multimeric complexes at the plasma membrane. This protein localizes to tight junctions and to the apical membrane of epithelial cells. A similar protein in Drosophila is a scaffolding protein which tethers several members of a multimeric signaling complex in photoreceptors. [provided by RefSeq]
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Gagnoux-Palacios L, Awina H, Audebert S, et al. Cell polarity and adherens junction formation inhibit epithelial Fas cell death receptor signaling. J Cell Biol. 2018,217(11):3839-3852. doi: 10.1083/jcb.201805071Read this paper
- Jiang X, An W, Yang X, et al. Asymmetric distribution of CRUMBS polarity complex proteins from compacted 8-cell to blastocyst stage during mouse preimplantation development. Gene Expr Patterns. 2018,27:93-98. doi: 10.1016/j.gep.2017.11.002Read this paper
- Lennon FE, Mirzapoiazova T, Mambetsariev N, et al. Transactivation of the receptor-tyrosine kinase ephrin receptor A2 is required for the low molecular weight hyaluronan-mediated angiogenesis that is implicated in tumor progression. J Biol Chem. 2014,289(35):24043-58. doi: 10.1074/jbc.M114.554766Read this paper




