Bio-Connect

PATJ antibody [N1], N-term

GTX104753
GeneTex
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman, Mouse
TargetPATJ
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Overview

  • Supplier
    GeneTex
  • Product Name
    PATJ antibody [N1], N-term
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID10207
  • Target name
    PATJ
  • Target description
    PATJ crumbs cell polarity complex component
  • Target synonyms
    channel-interacting PDZ domain protein; channel-interacting PDZ domain-containing protein; Cipp; hINADL; inactivation no after-potential D-like protein; inactivation-no-afterpotential D-like; INADL; InaD-like; inaD-like protein; PALS1-associated tight junction protein; PDZ domain protein; protein associated to tight junctions
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    This gene encodes a protein with multiple PDZ domains. PDZ domains mediate protein-protein interactions, and proteins with multiple PDZ domains often organize multimeric complexes at the plasma membrane. This protein localizes to tight junctions and to the apical membrane of epithelial cells. A similar protein in Drosophila is a scaffolding protein which tethers several members of a multimeric signaling complex in photoreceptors. [provided by RefSeq]
  • Reactivity
    Human, Mouse
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Cell polarity and adherens junction formation inhibit epithelial Fas cell death receptor signaling. Gagnoux-Palacios L et al., 2018 Nov 5, J Cell Biol
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  • Asymmetric distribution of CRUMBS polarity complex proteins from compacted 8-cell to blastocyst stage during mouse preimplantation development. Jiang X et al., 2018 Jan, Gene Expr Patterns
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  • Transactivation of the receptor-tyrosine kinase ephrin receptor A2 is required for the low molecular weight hyaluronan-mediated angiogenesis that is implicated in tumor progression. Lennon FE et al., 2014 Aug 29, J Biol Chem
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