PAX8 antibody
GTX101583
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetPAX8
Overview
- SupplierGeneTex
- Product NamePAX8 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:5000-1:20000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:500-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1.84 mg/ml
- ConjugateUnconjugated
- Gene ID7849
- Target namePAX8
- Target descriptionpaired box 8
- Target synonymsPAX-8, paired box protein Pax-8, paired domain gene 8
- HostRabbit
- IsotypeIgG
- Protein IDQ06710
- Protein NamePaired box protein Pax-8
- Scientific DescriptionThis gene encodes a member of the paired box (PAX) family of transcription factors. Members of this gene family typically encode proteins that contain a paired box domain, an octapeptide, and a paired-type homeodomain. This nuclear protein is involved in thyroid follicular development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas. Alternateively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Ito S, Yamaguchi Y, Kubota S, et al. Immunohistochemical identification of epithelial cell types in the isthmus of bovine oviduct: Comparison with the ampulla. J Reprod Dev. 2023,69(1):18-24. doi: 10.1262/jrd.2022-104Read this paper
- Hsu CF, Chen PC, Seenan V, et al. Ovulatory Follicular Fluid Facilitates the Full Transformation Process for the Development of High-Grade Serous Carcinoma. Cancers (Basel). 2021,13(3). doi: 10.3390/cancers13030468Read this paper
- Sun Z, Lu J, Wu M, et al. PTEN-knockdown disrupts the morphology, growth pattern and function of Nthy-Ori 3-1 cells by downregulating PAX8 expression. Oncol Lett. 2019,18(6):6732-6740. doi: 10.3892/ol.2019.11028Read this paper
- Shi K, Yin X, Cai MC, et al. PAX8 regulon in human ovarian cancer links lineage dependency with epigenetic vulnerability to HDAC inhibitors. Elife. 2019,8. doi: 10.7554/eLife.44306Read this paper


![IHC-P analysis of human thyroid gland tissue using GTX57191 PAX8 antibody [IHC008]](https://www.genetex.com/upload/website/prouct_img/normal/GTX57191/GTX57191_20180619_IHC-P_w_23061123_319.webp)

![IHC-P analysis of human renal cell carcinoma tissue using GTX34961 PAX8 antibody [PAX8/1491].](https://www.genetex.com/upload/website/prouct_img/normal/GTX34961/GTX34961_20200115_IHC-P_1083_w_23060801_505.webp)
![IHC-P analysis of human renal cell carcinoma tissue using GTX34962 PAX8 antibody [PAX8/1492].](https://www.genetex.com/upload/website/prouct_img/normal/GTX34962/GTX34962_20200115_IHC-P_1084_w_23060801_546.webp)
