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PAX8 antibody

GTX101583
GeneTex
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityCanine, Human, Mouse, Rat
TargetPAX8
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Overview

  • Supplier
    GeneTex
  • Product Name
    PAX8 antibody
  • Delivery Days Customer
    9
  • Antibody Specificity
    Based on sequence homology, this antibody may cross react with PAX1, PAX2, PAX5 or PAX6 protein.
  • Application Supplier Note
    WB: 1:5000-1:20000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:500-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1.84 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID7849
  • Target name
    PAX8
  • Target description
    paired box 8
  • Target synonyms
    paired box protein Pax-8; paired domain gene 8
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ06710
  • Protein Name
    Paired box protein Pax-8
  • Scientific Description
    This gene encodes a member of the paired box (PAX) family of transcription factors. Members of this gene family typically encode proteins that contain a paired box domain, an octapeptide, and a paired-type homeodomain. This nuclear protein is involved in thyroid follicular development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas. Alternateively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq]
  • Reactivity
    Canine, Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Immunohistochemical identification of epithelial cell types in the isthmus of bovine oviduct: Comparison with the ampulla.
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  • Ovulatory Follicular Fluid Facilitates the Full Transformation Process for the Development of High-Grade Serous Carcinoma. Hsu CF et al., 2021 Jan 26, Cancers (Basel)
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  • PTEN-knockdown disrupts the morphology, growth pattern and function of Nthy-Ori 3-1 cells by downregulating PAX8 expression. Sun Z et al., 2019 Dec, Oncol Lett
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  • PAX8 regulon in human ovarian cancer links lineage dependency with epigenetic vulnerability to HDAC inhibitors. Shi K et al., 2019 May 3, Elife
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