PAX8 antibody
GTX101583
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityCanine, Human, Mouse, Rat
TargetPAX8
Overview
- SupplierGeneTex
- Product NamePAX8 antibody
- Delivery Days Customer9
- Antibody SpecificityBased on sequence homology, this antibody may cross react with PAX1, PAX2, PAX5 or PAX6 protein.
- Application Supplier NoteWB: 1:5000-1:20000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:500-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1.84 mg/ml
- ConjugateUnconjugated
- Gene ID7849
- Target namePAX8
- Target descriptionpaired box 8
- Target synonymspaired box protein Pax-8; paired domain gene 8
- HostRabbit
- IsotypeIgG
- Protein IDQ06710
- Protein NamePaired box protein Pax-8
- Scientific DescriptionThis gene encodes a member of the paired box (PAX) family of transcription factors. Members of this gene family typically encode proteins that contain a paired box domain, an octapeptide, and a paired-type homeodomain. This nuclear protein is involved in thyroid follicular development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas. Alternateively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq]
- ReactivityCanine, Human, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Immunohistochemical identification of epithelial cell types in the isthmus of bovine oviduct: Comparison with the ampulla.Read more
- Ovulatory Follicular Fluid Facilitates the Full Transformation Process for the Development of High-Grade Serous Carcinoma. Hsu CF et al., 2021 Jan 26, Cancers (Basel)Read more
- PTEN-knockdown disrupts the morphology, growth pattern and function of Nthy-Ori 3-1 cells by downregulating PAX8 expression. Sun Z et al., 2019 Dec, Oncol LettRead more
- PAX8 regulon in human ovarian cancer links lineage dependency with epigenetic vulnerability to HDAC inhibitors. Shi K et al., 2019 May 3, ElifeRead more