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Paxilline

BS-75147C
Bioss Antibodies
Estimated Purity>95%
Product group Chemicals
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More than 130 suppliers
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Overview

  • Supplier
    Bioss Antibodies
  • Product Name
    Paxilline [57186-25-1]
  • Delivery Days Customer
    16
  • Certification
    Research Use Only
  • Estimated Purity
    >95%
  • Scientific Description
    Tremorgenic [1]. Potent, selective and reversible inhibitor of high-conductance calcium-activated potassium (BKCa) channels [2]. Reversible inhibitor of inositol 1,4,5-trisphosphate receptor (InsP(3)) [3]. Sarco/endoplasmic reticulum Ca2+ ATPase (SERCA) inhibitor [4]. Liver X receptor (LXRalpha and LXRbeta; NR1H3 and NR1H2) agonist in biochemical and in vitro cell-based assays [5]. Anticonvulsant [6]. Apoptosis enhancer. Can sensitize various glioma cells to TRAIL-mediated apoptosis [7]. Shown to protect neuronal cells against glutamate-induced cell death [8].
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200