Pazopanib-13C,d3

MedChem Express

Pazopanib-13C,d3

10

Research Use Only

C20 13CH20D3N7O2S

441.53

Pazopanib- 13 C,d 3 is the deuterium and 13 C labeled Pazopanib[1]. Pazopanib (GW786034) is a novel multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFRbeta, c-Kit, FGFR1, and c-Fms with IC50s of 10, 30, 47, 84, 74, 140 and 146 nM, respectively[2][3].

CC1=C2C(C=C(C=C2)N(C3=NC(NC4=CC(S(N)(=O)=O)=C(C=C4)C)=NC=C3)[13C]([2H])([2H])[2H])=NN1C

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