PBD dimer-2

MedChem Express

PBD dimer-2

10

Research Use Only

98.03

C31H36N4O6

560.64

PBD dimer-2 (compound 2c) is a C8-linked pyrrolobenzodiazepine dimer. PBD dimer-2 can span an extra base pair and cross-link the 5-Pu-GA(T/A)TC-Py sequence. PBD dimer-2 can be used as a payload for antibody-agent conjugates (ADCs), and it can be used for the research of cancer[1][2].

O=C1C2=CC(OC)=C(OCCCCCOC3=C(C=C4C(N=C[C@@]5([H])N(CCC5)C4=O)=C3)OC)C=C2N=C[C@@]6([H])N1CCC6

-20°C

41116133