PBRM1-BD2-IN-5 [2819989-61-0]
HY-151532
CAS Number2819989-61-0
Product group Chemicals
Estimated Purity99.75
Molecular Weight272.73
Overview
- SupplierMedChem Express
- Product NamePBRM1-BD2-IN-5 [2819989-61-0]
- Delivery Days Customer10
- CAS Number2819989-61-0
- CertificationResearch Use Only
- Estimated Purity99.75
- Molecular FormulaC15H13ClN2O
- Molecular Weight272.73
- Scientific DescriptionPBRM1-BD2-IN-5 is a potent PBRM1 Bromodomain inhibitor with Kd values of 1.5 microM and 3.9 microM for PBRM1-BD2 and PBRM1-BD5, respectively, and an IC50 value of 0.26 microM for PBRM1-BD2. PBRM1-BD2-IN-5 reduces the binding of full-length PBRM1 within the PBAF complex in cell lysates to acetylated histone peptide. PBRM1-BD2-IN-5 can be used to research anticancer[1].
- SMILESO=C1NC(C2=CC=CC(C)=C2)NC3=C1C(Cl)=CC=C3
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12131703