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PBT434 (mesylate)

HY-120475A
MedChem Express
Estimated Purity99.92
DownloadMSDS
Product group Chemicals
Molecular Weight398.26
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Overview

  • Supplier
    MedChem Express
  • Product Name
    PBT434 (mesylate)
  • Delivery Days Customer
    10
  • Certification
    Research Use Only
  • Estimated Purity
    99.92
  • Molecular Formula
    C13H17Cl2N3O5S
  • Molecular Weight
    398.26
  • Scientific Description
    PBT434 methanesulfonate is a potent, orally active and cross the blood-brain barrier alpha-synuclein aggregation inhibitor. PBT434 methanesulfonate can be used as a iron chelator and modulates transcellular iron trafficking. PBT434 methanesulfonate inhibits iron-mediated redox activity and iron-mediated aggregation of alpha-synuclein. PBT434 methanesulfonate prevents the loss of substantia nigra pars compacta neurons (SNpc). PBT434 methanesulfonate has the potential for the research of Parkinsons disease (PD) [1] [2] .
  • SMILES
    O=C1C2=C(N=C(CNCC)N1C)C(O)=C(Cl)C=C2Cl.O=S(O)(C)=O
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352200