PCDH12 antibody

GeneTex

PCDH12 antibody

9

This antibody is predicted to not cross-react with PCDH18.

WB: 1 microg/mL. IHC-P: 5 microg/mL. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

PCDH12

protocadherin 12

DMJDS1; protocadherin-12; vascular cadherin-2; vascular endothelial cadherin 2; VECAD2; VE-cad-2; VE-cadherin 2; VE-cadherin-2

Rabbit

IgG

Protocadherin-12

Protocadherins comprise the largest group within the cadherin family of calcium-dependent cell-cell adhesion molecules. Protocadherin 12 (PCDH12) was initially identified through PCR screening of mouse heart microvascular endothelial cell RNA; further experiments revealed its mRNA to be strongly expressed in highly vascularized organs such as lung and kidney, in addition to glycogen-rich trophoblasts in the placenta. PCDH12- mice are viable and fertile, but show reduced placental and embryonic sizes when compared to wild-type mice. Further studies showed significant expression changes in 2,289 genes, including those involved in tissue morphogenesis, angiogenesis, cell-matrix adhesion and migration, immune response and chromatin remodeling. This antibody is predicted to not cross-react with PCDH18.

Human, Mouse, Rat

-20°C or -80°C,2°C to 8°C

12352203