PCNA antibody [131-11964(19F4)]
GTX39739
ApplicationsImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Rat
TargetPCNA
Overview
- SupplierGeneTex
- Product NamePCNA antibody [131-11964(19F4)]
- Delivery Days Customer9
- Antibody SpecificityPCNA (Proliferating Cell Nuclear Antigen), formerly called Cyclin, is a 36 kDa proliferation associatedantigen.
- ApplicationsImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID131-11964(19F4)
- Concentration1.20 mg/ml
- ConjugateUnconjugated
- Gene ID5111
- Target namePCNA
- Target descriptionproliferating cell nuclear antigen
- Target synonymsATLD2; cyclin; DNA polymerase delta auxiliary protein; proliferating cell nuclear antigen
- HostMouse
- IsotypeIgG1
- Protein IDP12004
- Protein NameProliferating cell nuclear antigen
- Scientific DescriptionThe protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. [provided by RefSeq, Jul 2008]
- ReactivityHuman, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Mitotic activity, modulation of DNA processing, and purinergic signalling in the adult rat auditory brainstem following sensory deafferentation. Illing RB et al., 2019 Jul 20, Eur J NeurosciRead more