PCSK9, Mouse (660a.a, HEK293, His)

MedChem Express

PCSK9, Mouse (660a.a, HEK293, His)

10

Research Use Only

96.50

Proprotein convertase subtilisin/kexin type 9

The PCSK9 protein regulates cholesterol levels by degrading LDLR, VLDLR, LRP1/APOER, and LRP8/APOER2 receptors. It promotes LDLR degradation, inhibits recycling, induces ubiquitination, and affects APOB degradation. Additionally, PCSK9 influences BACE1 intermediates, ENaC surface expression, and neuronal apoptosis by modulating LRP8/APOER2 levels and anti-apoptotic signaling pathways. PCSK9 Protein, Mouse (660a.a, HEK293, His) is the recombinant mouse-derived PCSK9 protein, expressed by HEK293 , with C-His labeled tag. The total length of PCSK9 Protein, Mouse (660a.a, HEK293, His) is 660 a.a., with molecular weight of ~19 & 65 kDa, respectively.

-20°C

12352202