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PCSK9, Mouse (660a.a, HEK293, His)

Research Use Only
HY-P73339
MedChem Express
Protein IDQ80W65
Product group Proteins / Signaling Molecules
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Overview

  • Supplier
    MedChem Express
  • Product Name
    PCSK9, Mouse (660a.a, HEK293, His)
  • Delivery Days Customer
    10
  • Certification
    Research Use Only
  • Estimated Purity
    96.50
  • Protein IDQ80W65
  • Protein Name
    Proprotein convertase subtilisin/kexin type 9
  • Scientific Description
    The PCSK9 protein regulates cholesterol levels by degrading LDLR, VLDLR, LRP1/APOER, and LRP8/APOER2 receptors. It promotes LDLR degradation, inhibits recycling, induces ubiquitination, and affects APOB degradation. Additionally, PCSK9 influences BACE1 intermediates, ENaC surface expression, and neuronal apoptosis by modulating LRP8/APOER2 levels and anti-apoptotic signaling pathways. PCSK9 Protein, Mouse (660a.a, HEK293, His) is the recombinant mouse-derived PCSK9 protein, expressed by HEK293 , with C-His labeled tag. The total length of PCSK9 Protein, Mouse (660a.a, HEK293, His) is 660 a.a., with molecular weight of ~19 & 65 kDa, respectively.
  • Storage Instruction
    -20°C
  • UNSPSC
    12352202