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PD 151746 [179461-52-0]

PD 151746 [179461-52-0]

T2493
TargetMol Chemicals
CAS Number179461-52-0
Product group Chemicals
Estimated Purity≥98%
Molecular Weight237.25
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    PD 151746
  • Delivery Days Customer
    4
  • CAS Number
    179461-52-0
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    PD 151746
  • Estimated Purity
    ≥98%
  • Molecular Formula
    C11H8FNO2S
  • Molecular Weight
    237.25
  • Scientific Description
    PD151746 is a calpain inhibitor with a 20-fold selectivity for u-calpain (Ki = 0.26 +/- 0.03 microM) over m-calpain (Ki = 5.33 +/- 0.77 microM). Its IC50 values are 0.26 +/- 0.03 microM (Ki for micro-calpain) and 5.33 +/- 0.77 microM (Ki for m-calpain) [1]. In vitro, PD151746 targets calpain and reduces oxLDL-induced cytotoxicity [2].
  • Shelf life instruction
    3 years
  • SMILES
    OC(=O)C(S)=Cc1c[nH]c2ccc(F)cc12
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

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