PD-L1 Antibody / B7-H1 / CD274

Biorbyt

PD-L1 Antibody / B7-H1 / CD274

16

Optimal dilution of the antibody should be determined by the researcher.

ELISA (order BSA-free format for coating),Flow cytometry: 1-2ug/ml,Immunofluorescence: 1-2ug/ml ELISA, FACS, IF

Research Use Only

Monoclonal

PDL1/2743

Unconjugated

CD274

CD274 molecule

B7 homolog 1; B7-H; B7H1; CD274 antigen; hPD-L1; PDCD1 ligand 1; PDCD1L1; PDCD1LG1; PDL1; PD-L1; programmed cell death 1 ligand 1

Mouse

IgG2b

Programmed cell death 1 ligand 1

PD-L1 is a checkpoint regulator in immune cells, it is expressed on immune or non-hematopoietic cells. Expression of the protein is seen during pregnancy where it has a role in suppressing the immune system. PD-L1 induces an inhibitory signal in activated T-cells and promotes T-cell apoptosis. It is overexpressed in a number of different cancers where it is believed to play a significant role in the cancer s ability to evade the immune system.

Human

-20°C,2°C to 8°C

12352203