PD0166285 (dihydrochloride) [212391-63-4]

MedChem Express

PD0166285 (dihydrochloride) [212391-63-4]

10

212391-63-4

Research Use Only

C26H29Cl4N5O2

585.35

PD0166285 dihydrochloride, a substrate of P-gp, is a WEE1 inhibitor and a weak Myt1 inhibitor with IC50 values of 24 and 72 nM, respectively. PD0166285 dihydrochloride exhibits an IC50 of 3.433 microM for Chk1[1].

O=C1N(C)C2=NC(NC3=CC=C(OCCN(CC)CC)C=C3)=NC=C2C=C1C4=C(Cl)C=CC=C4Cl.[H]Cl.[H]Cl

12352200