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PDCD1 / PD1 / CD279 (Programmed Cell Death 1) (PDCD1/1410R), CF640R conjugate, 0.1mg/mL [26628-22-8]

BNC401410
Biotium
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityBovine, Human, Rabbit
TargetPDCD1
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Overview

  • Supplier
    Biotium
  • Product Name
    PDCD1 / PD1 / CD279 (Programmed Cell Death 1) (PDCD1/1410R), CF640R conjugate, 0.1mg/mL
  • Delivery Days Customer
    9
  • Applications
    ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    PDCD1/1410R
  • Concentration
    0.1 mg/ml
  • Conjugate
    Other Conjugate
  • Gene ID5133
  • Target name
    PDCD1
  • Target description
    programmed cell death 1
  • Target synonyms
    CD279; hPD-1; hPD-l; hSLE1; PD1; PD-1; programmed cell death 1 protein; programmed cell death protein 1; protein PD-1; SLEB2; systemic lupus erythematosus susceptibility 2
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ15116
  • Protein Name
    Programmed cell death protein 1
  • Scientific Description
    PD-1 (also known as Programmed Death 1, CD279, and PDCD1) is a negative regulatory T-cell surface receptor. PD-1 is a Type I transmembrane protein expressed on the plasma membrane of T-cells. It is a T-cell checkpoint protein, involved in preventing autoimmunity. Because binding of PD-1 by its ligands PD-L1 or PD-L2 has a suppressive effect on the immune system, inhibition of the PD-1/PD-L1 pathway is a major strategy of immune-oncology therapies. PD-L1 is upregulated in certain cancers, and blocking PD-1 or PD-L1 can inhibit cancer growth. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
  • Source
    Animal
  • Reactivity
    Bovine, Human, Rabbit
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203