PDCD6 Polyclonal Antibody

Reddot Biotech

PDCD6 Polyclonal Antibody

5

ImmunoFluorescence, Western Blot, ImmunoHistoChemistry

Research Use Only

1 mg/ml

Unconjugated

PDCD6

programmed cell death 6

ALG2; ALG-2; apoptosis-linked gene 2 protein homolog; PEF1B; probable calcium-binding protein ALG-2; programmed cell death protein 6

Rabbit

IgG

This gene encodes a calcium-binding protein belonging to the penta-EF-hand protein family. Calcium binding is important for homodimerization and for conformational changes required for binding to other protein partners. This gene product participates in T cell receptor-, Fas-, and glucocorticoid-induced programmed cell death. In mice deficient for this gene product, however, apoptosis was not blocked suggesting this gene product is functionally redundant. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is also located on the short arm of chromosome 5.

Human, Mouse, Rat

-20°C

12352203