Bio-Connect

PDE11A Polyclonal Antibody

RD266697A
Reddot Biotech
ApplicationsImmunoFluorescence
Product group Antibodies
ReactivityMouse, Rat
TargetPDE11A
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Overview

  • Supplier
    Reddot Biotech
  • Product Name
    PDE11A Polyclonal Antibody
  • Delivery Days Customer
    5
  • Applications
    ImmunoFluorescence
  • Certification
    Research Use Only
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID50940
  • Target name
    PDE11A
  • Target description
    phosphodiesterase 11A
  • Target synonyms
    cAMP and cGMP cyclic nucleotide phosphodiesterase 11A; dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A; PPNAD2
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    The 3,5-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3,5-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a member of the PDE protein superfamily. Mutations in this gene are a cause of Cushing disease and adrenocortical hyperplasia. Multiple transcript variants encoding different isoforms have been found for this gene.
  • Reactivity
    Mouse, Rat
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203