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IHC analysis of human ovarian medulla tissue using GTX14602 PDE1C antibody. Dilution : 1:1500
IHC analysis of human ovarian medulla tissue using GTX14602 PDE1C antibody. Dilution : 1:1500
IHC analysis of human ovarian medulla tissue using GTX14602 PDE1C antibody. Dilution : 1:1500

PDE1C antibody

GTX14602
GeneTex
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry
Product group Antibodies
TargetPDE1C
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Overview

  • Supplier
    GeneTex
  • Product Name
    PDE1C antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:2000. ICC/IF: 1:40-1:100. IP: 1:200. ELISA: 1:10000. IHC: 1:40-1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.5 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID5137
  • Target name
    PDE1C
  • Target description
    phosphodiesterase 1C
  • Target synonyms
    3',5'-cyclic-AMP phosphodiesterase; 3',5'-cyclic-GMP phosphodiesterase; calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C; cam-PDE 1C; DFNA74; Hcam3; hCam-3; Human 3',5' cyclic nucleotide phosphodiesterase (HSPDE1C1A); phosphodiesterase 1C, calmodulin-dependent 70kDa
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ14123
  • Protein Name
    Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C
  • Scientific Description
    This gene encodes an enzyme that belongs to the 35-cyclic nucleotide phosphodiesterase family. Members of this family catalyze hydrolysis of the cyclic nucleotides, cyclic adenosine monophosphate and cyclic guanosine monophosphate, to the corresponding nucleoside 5-monophosphates. The enzyme encoded by this gene regulates proliferation and migration of vascular smooth muscle cells, and neointimal hyperplasia. This enzyme also plays a role in pathological vascular remodeling by regulating the stability of growth factor receptors, such as PDGF-receptor-beta. [provided by RefSeq, Jul 2016]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • HPRT-deficiency dysregulates cAMP-PKA signaling and phosphodiesterase 10A expression: mechanistic insight and potential target for Lesch-Nyhan Disease? Guibinga GH et al., 2013, PLoS One
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