PDE4A (phospho Ser140) antibody

GeneTex

PDE4A (phospho Ser140) antibody

9

This antibody detects all known long-form variants of PDE4A, including PDE4A4, PDE4A5, PDE4A8, PDE4Ax when phosphorylated at the PKA phosphorylation site. It will not cross-react with PDE4A phosphorylated at the ERK phosphorylation site. It does not cross

WB: 1:500. IP: 1:150. ELISA: 1:10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoPrecipitation, Western Blot, ELISA

Research Use Only

Polyclonal

0.57 mg/ml

Unconjugated

PDE4A

phosphodiesterase 4A

cAMP-specific 3',5'-cyclic phosphodiesterase 4A; DPDE2; PDE4; PDE46; phosphodiesterase 4A, cAMP-specific (dunce; phosphodiesterase E2 dunce homolog, Drosophila; phosphodiesterase isozyme 4

Rabbit

IgG

cAMP-specific 3',5'-cyclic phosphodiesterase 4A

The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011]

Human, Mouse, Rabbit, Rat

-20°C or -80°C,2°C to 8°C

12352203