Bio-Connect

PDE6A Polyclonal Antibody

RD267927A
Reddot Biotech
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetPDE6A
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Overview

  • Supplier
    Reddot Biotech
  • Product Name
    PDE6A Polyclonal Antibody
  • Delivery Days Customer
    5
  • Applications
    Western Blot
  • Certification
    Research Use Only
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID5145
  • Target name
    PDE6A
  • Target description
    phosphodiesterase 6A
  • Target synonyms
    cGMP phosphodiesterase alpha subunit; CGPR-A; GMP-PDE alpha; PDE V-B1; PDEA; phosphodiesterase 6A, cGMP-specific, rod, alpha; retinitis pigmentosa type 43; rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha; rod photoreceptor cGMP phosphodiesterase alpha subunit; RP43
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    This gene encodes the cyclic-GMP (cGMP)-specific phosphodiesterase 6A alpha subunit, expressed in cells of the retinal rod outer segment. The phosphodiesterase 6 holoenzyme is a heterotrimer composed of an alpha, beta, and two gamma subunits. cGMP is an important regulator of rod cell membrane current, and its dynamic concentration is established by phosphodiesterase 6A cGMP hydrolysis and guanylate cyclase cGMP synthesis. The protein is a subunit of a key phototransduction enzyme and participates in processes of transmission and amplification of the visual signal. Mutations in this gene have been identified as one cause of autosomal recessive retinitis pigmentosa.
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203