PDE6A Polyclonal Antibody
RD267927A
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetPDE6A
Overview
- SupplierReddot Biotech
- Product NamePDE6A Polyclonal Antibody
- Delivery Days Customer5
- ApplicationsWestern Blot
- CertificationResearch Use Only
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID5145
- Target namePDE6A
- Target descriptionphosphodiesterase 6A
- Target synonymscGMP phosphodiesterase alpha subunit; CGPR-A; GMP-PDE alpha; PDE V-B1; PDEA; phosphodiesterase 6A, cGMP-specific, rod, alpha; retinitis pigmentosa type 43; rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha; rod photoreceptor cGMP phosphodiesterase alpha subunit; RP43
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThis gene encodes the cyclic-GMP (cGMP)-specific phosphodiesterase 6A alpha subunit, expressed in cells of the retinal rod outer segment. The phosphodiesterase 6 holoenzyme is a heterotrimer composed of an alpha, beta, and two gamma subunits. cGMP is an important regulator of rod cell membrane current, and its dynamic concentration is established by phosphodiesterase 6A cGMP hydrolysis and guanylate cyclase cGMP synthesis. The protein is a subunit of a key phototransduction enzyme and participates in processes of transmission and amplification of the visual signal. Mutations in this gene have been identified as one cause of autosomal recessive retinitis pigmentosa.
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C
- UNSPSC12352203