PDEdelta autophagic degrader 1

MedChem Express

PDEdelta autophagic degrader 1

14

Research Use Only

C41H42Br2IN7O5

999.53

PDEdelta autophagic degrader 1 (compound 12c), an autophagosome-tethering compound (ATTEC) . is a potent PDEdelta autophagic degrader. PDEdelta autophagic degrader 1 reduces the PDEdelta protein level through lysosome-mediated autophagy without affecting the PDEdelta mRNA expression. PDEdelta autophagic degrader 1 suppresses the growth in KRAS mutant pancreatic cancer cells [1] .

O=C(NCCCCCCNC(COC1=C(Br)C=C(/C=C2C(NC3=C\2C=C(I)C=C3)=O)C=C1Br)=O)CCCN4N=C(C)C5=C(C)N(C6=CC=C(C)C=C6)N=C5C4=O

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