PDGF Receptor beta antibody [18A2]

GeneTex

PDGF Receptor beta antibody [18A2]

9

Flow Cytometry, ImmunoFluorescence, ImmunoCytoChemistry

Research Use Only

Monoclonal

18A2

1 mg/ml

Unconjugated

PDGFRB

platelet derived growth factor receptor beta

CD140B, IBGC4, IMF1, JTK12, KOGS, OPDKD, PDGFR, PDGFR-1, PDGFR1, PENTT, platelet-derived growth factor receptor beta, Activated tyrosine kinase PDGFRB, CD140 antigen-like family member B, NDEL1-PDGFRB, PDGF-R-beta, PDGFR-beta, beta-type platelet-derived growth factor receptor, platelet-derived growth factor receptor 1, platelet-derived growth factor receptor, beta polypeptide

Mouse

IgG1

Platelet-derived growth factor receptor beta

The protein encoded by this gene is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer (PDGFB or PDGFD) or a heterodimer (PDGFA and PDGFB). This gene is essential for normal development of the cardiovascular system and aids in rearrangement of the actin cytoskeleton. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the ETV6 gene, results in chronic myeloproliferative disorder with eosinophilia. [provided by RefSeq, Aug 2017]

2°C to 8°C

12352203